Figure 5.
The role of resveratrol as an oligoprotective agent; Resveratrol activates the Nrf2/ HO-1 signaling pathway, resulting in a decrease in oxygen free radicals and NFκB inflammatory factor followed by increased GDNF, BDNF and TGF-β resulting in increased oligodendrocyte viability
Nrf2: Nuclear factor erythroid 2-related factor 2; HO-1: Heme oxygenase 1.