Table 1.
DBS Patient Demographics
| Patient | Age (Years) | Sex | Time Since Diagnosis (Years) | Pre-Op MDS-UPDRS III (off meds) | Pre-Op MDS-UPDRS III (on meds) | MDS-UPDRS III (ON STN DBS, off meds) | LEDD (mg) |
|---|---|---|---|---|---|---|---|
| 1* | 72.9 | M | 9.9 | 54 | 41 | 24 | 1098 |
| 2** | 52.8 | M | 4.9 | 24 | 8 | 5 | 1314 |
| 3** | 62.5 | M | 3.0 | 35 | 26 | 11 | 400 |
| 4** | 65.7 | M | 5.2 | 29 | 16 | 12 | 500 |
| 5** | 58.1 | M | 3.4 | 39 | 23 | 19 | 1923 |
| 6** | 42.2 | M | 4.5 | 58 | 12 | 9 | 1200 |
| 7* | 69.0 | M | 10.6 | 41 | 28 | 14 | 1116 |
| 8** | 53.5 | M | 7.6 | 52 | 29 | 17 | 2405 |
| 9 | 73.1 | F | 8.8 | 37 | 22 | 18 | 1588 |
| 10** | 72.2 | M | 8.9 | 47 | 23 | 29 | 750 |
| 11** | 58.6 | F | 10.0 | 33 | 6 | 18 | 1000 |
| 12* | 54.5 | M | 11.0 | 56 | 20 | 20 | 1710 |
| 13 | 34.3 | M | 2.1 | 59 | 22 | 35 | 950 |
| 14* | 57.3 | M | 6.1 | 62 | 23 | 19 | 1075 |
| 15** | 67.6 | F | 6.1 | 44 | 25 | 2 | 825 |
| 16* | 50.6 | F | 9.2 | 50 | 26 | 14 | 920 |
| 17* | 61.9 | M | 14.3 | 42 | 24 | 8 | 1200 |
| 18** | 52.0 | F | 12.5 | 34 | 6 | 6 | 650 |
| 19 | 66.1 | M | 7.6 | 51 | 10 | 16 | 875 |
| 20** | 56.8 | F | 11.6 | 38 | 18 | 8 | 1125 |
| 21 | 75.7 | F | 8.5 | 44 | 19 | 23 | 800 |
| 22* | 55.0 | M | 10.4 | 11 | 7 | 2 | 917 |
| 23* | 50.1 | M | 10.2 | 38 | 31 | 17 | 375 |
|
| |||||||
| Average ± SD | 59.2 ± 10.1 | 8.1 ± 3.2 | 42.5 ± 11.9 | 20.2 ± 8.7 | 15.0 ± 8.1 | 1074.6 ± 479.5 | |
*
indicates that the participant performed the SIP ON DBS.
**
indicates that the participant performed the SIP ON DBS and completed the three-year follow-up visit. LEDD: Levodopa Equivalent daily dose