Table 7. Univariate and multivariate analysis on factors for late mortality in hospital survivors.
| Characteristics | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Age(≥65y) | 2.051 | 1.001–4.203 | 0.050 | N/A | 0.460 | ||
| Female gender | 1.727 | 0.910–3.275 | 0.095 | N/A | 0.084 | ||
| Hypertension | 2.317 | 1.025–5.238 | 0.044 | 3.040 | 1.124–8.227 | 0.029 | |
| BMI ≥24 | 1.738 | 0.906–3.333 | 0.096 | N/A | 0.156 | ||
| Duration of hypertension | 1.057 | 1.018–1.098 | 0.004 | 1.042 | 0.994–1.092 | 0.087 | |
| Regular treatment of hypertension | 0.314 | 0.123–0.801 | 0.015 | 0.227 | 0.087–0.589 | 0.002 | |
| DBP at admission | 1.028 | 1.004–1.052 | 0.020 | N/A | 0.278 | ||
| Mean BP at admission | 1.021 | 1..000–1.042 | 0.045 | N/A | 0.428 | ||
| Beta blocker | 0.424 | 0.166–1.082 | 0.073 | 0.328 | 0.126–0.853 | 0.022 | |
| Diuretic | 0.244 | 0.034–1.777 | 0.164 | N/A | |||
| SBP at admission | 1.010 | 0.996–1.023 | 0.160 | N/A | |||
| Uncontrolled hypertension | 1.047 | 0.741–2.670 | 0.296 | N/A | |||
| Calcium channel blocker | 0.503 | 0.179–1.413 | 0.192 | N/A | |||
| ACEI or ARB | 0.573 | 0.177–1.859 | 0.354 | N/A | |||
| Other medication | 1.786 | 0.790–4.037 | 0.164 | N/A | |||
| Previous coronary artery disease | 1.514 | 0.365–6.238 | 0.567 | N/A | |||
| Cerebrovascular disease | 2.537 | 0.782–8.231 | 0.121 | N/A | |||
| sCr | 1.001 | 0.998–1.003 | 0.559 | N/A | |||
| WBC | 0.944 | 0.868–1.027 | 0.182 | N/A | |||
| PLT | 0.998 | 0.993–1.003 | 0.458 | N/A | |||
| Triglyceride | 0.806 | 0.527–1.232 | 0.319 | N/A | |||
| LVEF | 0.987 | 0.905–1.077 | 0.768 | N/A | |||
| Pericardial effusion | 2.523 | 0.777–8.189 | 0.123 | N/A | |||
| TAR | 0.719 | 0.351–1.472 | 0.367 | N/A | |||
| CPB time | 1.000 | 0.995–1.004 | 0.923 | N/A | |||
| Aortic valve | 1.009 | 0.520–1.955 | 0.980 | N/A | |||
| DHCA time | 0.980 | 0.957–1.004 | 0.105 | N/A | |||
| Drainage volume 24 hours after surgery | 1.000 | 0.999–1.001 | 0.901 | N/A | |||
| Ventilation time | 1.000 | 0.992–1.007 | 0.971 | N/A | |||
| ICU stay time | 1.003 | 0.986–1.019 | 0.761 | N/A | |||
| Hospital stay time | 1.000 | 0.973–1.028 | 0.994 | N/A | |||
HR, hazard ratio; CI, confidence interval; BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blocker; TAR, total arch replacement; SCr, serum creatinine; WBC, white blood cell; PLT, platelet; LVEF, left ventricular ejection fraction; CPB, cardiopulmonary bypass; DHCA, hypothermic circulatory arrest; ICU, intensive care unit; N/A, not available.