Table 3. Selected Current Clinical Trials of Immunotherapy for Early Stage Lung Cancer.
Study | Drug | Trial Phase | Treatment Arm(s) | Enrollment (actual or planned) | Primary Endpoint |
---|---|---|---|---|---|
NCT03833154 (PACIFIC-4) | Durvalumab | 3 | SBRT +/- adjuvant Durvalumab | 706 | PFS |
NCT03110978 (I-SABR) | Nivolumab | 2 | SBRT +/- adjuvant Nivolumab | 140 | EFS |
NCT03924869 (KEYNOTE-867) | Pembrolizumab | 3 | SBRT +/- concurrent and adjuvant Pembrolizumab | 530 | OS and EFS |
SBRT, stereotactic body radiation therapy; PFS, progression-free survival; EFS, event-free survival; OS, overall survival.