Table 3. Association between cardiac troponin I and incident outcomes.
| Item | No. of patients | No. of patients with events | Unadjusted HR (95% CI) | Adjusted HR (95% CI) |
|---|---|---|---|---|
| cTnI-1 | 633 | 101 | 1.62 (1.237–2.122) | 1.598 (1.158–2.204) |
| ≥0.065 (cutoff) | 154 | 89 | 2.7 (1.434–5.084) | 3.275 (1.613–6.651) |
| <0.065 | 479 | 12 | Reference | – |
| cTnI-2 | 633 | 101 | 1.483 (1.252–1.757) | 1.499 (1.228–1.831) |
| ≥0.395 (cutoff) | 141 | 46 | 3.847 (2.453–6.034) | 3.541 (2.177–5.759) |
| <0.395 | 492 | 55 | Reference | – |
| Absolute change | 633 | 101 | 1.378 (1.191–1.595) | 1.381 (1.138–1.674) |
| ≥0.143 (cutoff) | 224 | 55 | 2.568 (1.667–3.956) | 2.427 (1.527–3.856) |
| <0.143 | 409 | 46 | Reference | – |
The cutoff value was identified by the maximum Youden index value. HR, hazard ratio; CI, confidence interval; cTnI-1, measurement of cardiac troponin I levels less than 1 hour after CABG; cTnI-2, measurement of cardiac troponin I levels between 12–18 hours after coronary artery bypass grafting.