Table 3.

Comparisons of gEUD calculations (target volumes and normal tissues) for TG‐166 test cases between TPS results and those obtained from Mobius3D and COMPASS

		Differences (%)
TPS Values	M3D	CC	CR
	Benchmark Phantom
PTV Rectangle (as target)	73.6	$-0.8$	$-0.1$	$-0.3$
PTV Rectangle (as normal tissue)	56.1	0.7	1.0	0.7
Rectangle 1 (as target)	72.1	$-1.2$	$-0.2$	$-0.1$
Rectangle 1 (as normal tissue)	55.7	1.1	$-2.2$	$-2.4$
Rectangle 2	50.1	$-0.4$	1.4	1.5
Triangle 1	40.9	2	2.6	2.7
	Head & Neck
PTV 70	72.2	0.0	0.0	$-1.0$
PTV 54	59,4	$-1.0$	$-1.1$	$-1.7$
PTV 50	52.9	$-4.2$	$-0.4$	$-3.3$
Cord	35.5	$-0.9$	$-0.7$	$-1.1$
Left Parotid	20.4	0.8	5.2	$-2.6$
Right Parotid	19.9	$-3.4$	1.6	$-5.0$
Mandible	45.3	6.9	2.4	0.5
	Prostate
PTV	69.7	0.3	0.4	0.7
Rectum	42.7	4.1	0.9	4.3
Bladder	43.1	$-1.3$	$-0.2$	$-2.6$
Left Femoral Head	13.9	0.1	3.6	1.0
Right Femoral Head	14.2	$-0.5$	2.4	1.7
Pubic Bone	39.6	2.8	3.4	$-1.9$
	Brain
GTV 54	56.3	$-0.3$	0.2	0.0
PTV 50.4	54.5	0.9	0.1	$-0.2$
Brain Stem	41.5	0.3	$-0.8$	1.1
Optic Chiasm	46.5	$-0.8$	0.0	$-2.5$
Left Eye	11.0	0.0	1.6	$-7.7$
Right Eye	11.1	$-0.8$	1.6	$-2.6$
Left Optic Nerve	29.5	7.4	1.5	$-8.3$
Right Optic Nerve	33.8	3.2	2.6	$-6.0$
Left Inner Ear	35.2	8.8	3.2	5.3
Right Inner Ear	43.5	9.3	4.0	5.5
		M3D vs. CC	M3D vs. CR	CC vs. CR
	p‐values	0.93	$<0.05$	$<0.05$

$\mathrm{M}3\mathrm{D}=\text{Mobius}3\mathrm{D}$; $\text{CC}=\text{COMPASS dose calculation}$; $\text{CR}=\text{COMPASS dose reconstruction}$.