Figure 1.

An example of a theragnostic pairing of radiopharmaceuticals in a child with metastatic neuroblastoma. Diagnostic ¹²³I-mIBG imaging (A) anterior and (B) posterior views of whole-body planar scintigraphy demonstrating pathological uptake in a large left sided retroperitoneal mass as well as in metastatic disease in the femora and jaw, as well as physiological uptake in the salivary glands, heart, liver, urinary bladder and (despite blockade) in the thyroid gland. Corresponding (C) anterior and (D) posterior images following ¹³¹I-mIBG therapy administration showing uptake of the agent in the tumour and metastases as well as in physiological sites.