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. 2020 Nov 25;12(4):401–409. doi: 10.4274/jcrpe.galenos.2020.2020.0134

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©Copyright 2020 by Turkish Pediatric Endocrinology and Diabetes Society | The Journal of Clinical Research in Pediatric Endocrinology published by Galenos Publishing House.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Interaction network of genes targeted by micro-RNA 34a (miR-34a) and playing a significant role in endothelial function. This analysis was done using (miRTargetLinkdatabase) (https://ccb-web.cs.uni-saarland.de/mirtargetlink/index.php) and retrieved that miR-34a is the only miRNA that targets the three major genes, vascular endothelial growth factor, sirtuin 1 (SIRT1) and p53, involved in endothelial function (green line indicates a strong interaction and red line indicates a weak interaction)