Table 1.
Geographic distribution of rheumatoid arthritis-associated human leukocyte antigen (HLA)-DRB1 shared epitope alleles.
| Population | HLA-DRB1 Allele(s) | Sequence (70–74 Position) |
|---|---|---|
| Caucasoid | * 04:01/* 04:04, * 04:08 | QKRAA/QRRAA |
| Asian | * 04:05 | QRRAA |
| Native Americans | * 14:02 | QRRAA |
| African Americans | * 01:01, * 04:05/* 10:01 | QRRAA/RRRAA |
| Israeli Jews | * 01:01, * 01:02 | QRRAA |
| Latin Americans | * 04:01/* 04:04, * 04:05 | QKRAA/QRRAA |
*: HLA-DRB1 Allele.