Table 3.
Demographic and laboratory characters of the studied cases according to genotype distribution
| Genotypes |
|||||
|---|---|---|---|---|---|
| AA n = 420 |
GA n = 288 |
GG n = 192 |
test of significance | within group significant | |
| Age/years Mean±SD |
55.43 ± 11.08 | 50.13 ± 11.94 | 43.0 ± 8.09 | F = 7.37 P = .001* |
P1 = 0.069 P2 < 0.001* P3 = 0.045* |
| Sex Male Female |
192(45.7) 228(54.3) |
216(75.0) 72(25.0) |
96(50.0) 96(50.0) |
χ2 = 5.25 P = .072 |
P1 = 0.03* P2 = 0.776 P3 = 0.104 |
| DM -VE +VE |
312(74.3) 108(25.7) |
144(50.0) 144(50.0) |
156(81.2) 36(18.8) |
χ2 = 5.50 P = .064 |
P1 = 0.056 P2 = 0.586 P3 = 0.046* |
| HTN -VE +VE |
324(77.1) 96(22.9) |
252(87.5) 36(12.5) |
132(68.8) 60(31.2) |
χ2 = 2.10 P = .350 |
P1 = 0.316 P2 = 0.523 P3 = 0.146 |
| Smoking -VE +VE |
312(74.3) 108(25.7) |
276(95.8) 12(4.2) |
168(87.5) 24(12.5) |
χ2 = 5.10 P = .078 |
P1 = 0.03* P2 = 0.287 P3 = 0.327 |
| White blood cell count | 4.62 ± 1.53 4.5(3.3–5.5) |
5.16 ± 2.18 4.4(3.92–7.07) |
4.58 ± 2.05 4.4(2.6–5.7) |
KWχ2 = 0.461 P = .794 |
P1 = 0.740 P2 = 0.655 P3 = 0.507 |
| Haemoglobin (gm/dl) |
11.98 ± 1.13 | 11.84 ± 2.80 | 12.65 ± 1.29 | F = 1.01 P = .369 |
P1 = 0.778 P2 = 0.234 P3 = 0.180 |
| Lymphocytes | 1105.43 ± 650.77 900(600–1400) |
1655.83 ± 695.84 1850(942.5–2192.5) |
1900.81 ± 697.29 1950(1575–2275) |
KWχ2 = 45.37 P = .001* |
P1 = 0.005* P2 < 0.001* P3 = 0.287 |
| C-reactive protein (mg/L) | 42.29 ± 28.98 32(24–48) |
34.95 ± 31.28 24(12–48) |
21.56 ± 14.85 12(12–32) |
KWχ2 = 6.84 P = .03* |
P1 = 0.150 P2 = 0.009* P3 = 0.304 |
| Ferritin(ng/ml) | 433.40 ± 218.68 423(300–543) |
287.50 ± 166.94 278.5(148.5–366.5) |
212.69 ± 89.48 199(123.25–288.75) |
KWχ2 = 18.07 P = .001* |
P1 = 0.004* P2 < 0.001* P3 = 0.119 |
| D-dimer(mg/L) | 2.063 ± 3.89 1.23(0.80–1.68) |
1.26 ± 0.57 1.05(0.825–1.70) |
1.33 ± 0.55 1.20(0.90–1.7) |
KWχ2 = 0.55 P = .760 |
P1 = 0.567 P2 = 0.919 P3 = 0.462 |
P1:difference between GG & GA, P2: difference between GG & AA, P3: difference between GA & AA
KWχ2:Kruskal Wallis test, F: One Way ANOVA test, χ2:Chi-Square test, Parameters described as mean± SD, Median (interquartile range).