Table 4.
Disease severity and prognosis in different genotypes of the studied cases
| Genotypes |
|||||
|---|---|---|---|---|---|
| AA n = 420 |
GA n = 288 |
GG n = 192 |
test of significance | within group significant | |
| Severity of disease Mild severe |
84(20.0) 336(80.0) |
168(58.3) 120(41.7) |
192(100.0) 0(0.00) |
χ2 = 29.26 P = .001* |
P1 = 0.003* P2 < 0.001* P3 = 0.003* |
| Duration till first swab negative (days) | 13.91 ± 5.23 13(11–18) |
10.67 ± 5.39 9(6.25–15.75) |
6.31 ± 2.63 6(4–7.75) |
KWχ2 = 21.45 P = .001* |
P1 = 0.026* P2 < 0.001* P3 = 0.007* |
| Duration till second swab negative(days) | 21.74 ± 6.79 21(17–27) |
17.71 ± 7.47 14(12–25.5) |
11.94 ± 2.72 11(11–1.75) |
KWχ2 = 22.69 P = .001* |
P1 = 0.029* P2 < 0.001* P3 = 0.012* |
| Mechanical Ventilation -VE +VE |
300(71.4) 120(28.6) |
276(95.8) 12(4.2) |
192(100.0) 0(0.0) |
MC P = .006* |
P1 = 0.018* P2 = 0.017* P3 = 0.408 |
| Survival Survived Died |
360(85.7) 60(14.3) |
288(100.0) 0(0.0) |
192(100.0) 0(0.0) |
MC P = .047* |
P1 = 0.053 P2 = 0.111 P3 = … … …. |
P1:difference between GG & GA, P2: difference between GG & AA, P3: difference between GA & AA
KWχ2:Kruskal Wallis test MC: Monte Carlo test χ2:Chi-Square test, Parameters described as mean± SD, Median (interquartile range), number (percentage)