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. 2020 Nov 13;10(4):226. doi: 10.3390/jpm10040226

Table 3.

Patient survival after short-course radiotherapy vs. long-course radiotherapy.

All Patients
Univariate Multivariate
HR 1 (95% CI) p-value HR 1 (95% CI) p-value
Overall survival 0.55 (0.38–0.80) 0.002 0.59 (0.41–0.87) 0.007
Cancer-specific survival 0.47 (0.30–0.73) <0.001 0.57 (0.37–0.90) 0.016
Disease-free survival 0.54 (0.36–0.80) 0.002 0.62 (0.41–0.93) 0.021
Distant-recurrence-free survival 0.52 (0.34–0.79) 0.002 0.58 (0.38–0.90) 0.014
Local-recurrence-free survival 0.41 (0.18–0.91) 0.028 0.48 (0.21–1.08) 0.076
NMAC
Univariate Multivariate
HR 1 (95% CI) p-value HR 1 (95% CI) p-value
Overall survival 0.53 (0.35–0.80) 0.003 0.57 (0.37–0.88) 0.011
Cancer-specific survival 0.43 (0.26–0.72) 0.001 0.52 (0.30–0.88) 0.014
Disease-free survival 0.46 (0.30–0.72) <0.001 0.46 (0.29–0.74) 0.001
Distant-recurrence-free survival 0.45 (0.28–0.72) <0.001 0.44 (0.27–0.72) 0.001
Local-recurrence-free survival 0.39 (0.17–0.93) 0.033 0.45 (0.19–1.07) 0.070
MAC
Univariate Multivariate
HR 1 (95% CI) p-value HR 1 (95% CI) p-value
Overall survival 0.86 (0.37–2.03) 0.736 0.50 (0.19–1.30) 0.157
Cancer-specific survival 0.94 (0.39–2.27) 0.896 0.54 (0.28–2.34) 0.209
Disease-free survival 1.55 (0.62–3.86) 0.347 1.22 (0.45–3.29) 0.696
Distant-recurrence-free survival 1.49 (0.60–3.72) 0.393 1.33 (0.50–3.52) 0.572
Local-recurrence-free survival 0.49 (0.04–5.36) 0.555 - 2 - 2

1 Long-course radiotherapy is reference. Covariates entered in the multivariate model were sex, age, TNM stage, the grade of differentiation and perioperative chemotherapy. 2 Multivariate analysis was unavailable due to too few cases.