Table 3.
Logistic analysis of clinicopathological features associated with lymph node metastasis (pN1)
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p value | OR | 95% CI | p value | |
| Age (years) | ||||||
| ≤60 | 1 | 1 | ||||
| >60 | 0.66 | 0.49–0.90 | 0.008 | 0.663 | 0.48–0.91 | 0.011 |
| Gender | ||||||
| Male | 1 | 1 | ||||
| Female | 1.66 | 1.19–2.31 | 0.003 | 1.59 | 1.14–2.23 | 0.007 |
| Body mass index (kg/m2) | ||||||
| < 24 | 1 | |||||
| ≥ 24 | 1.29 | 0.76–2.04 | 0.915 | |||
| American Society of Anesthesiologists | ||||||
| 1–2 | 1 | |||||
| 3–4 | 1.21 | 0.48–2.45 | 0.621 | |||
| Tumor size | ||||||
| ≤3.0 cm | 1 | 1 | ||||
| >3.0 cm | 1.85 | 1.08–3.19 | 0.026 | 1.92 | 1.10–3.35 | 0.023 |
| Tumor location | ||||||
| Upper third | 1 | |||||
| Middle third | 1.53 | 0.72–3.24 | 0.271 | |||
| Lower third | 1.87 | 1.08–3.24 | 0.027 | |||
| Two thirds or more | 2.11 | 0.43–10.41 | 0.360 | |||
| Histologic type | ||||||
| Differentiated | 1 | |||||
| Undifferentiated | 1.27 | 0.94–1.71 | 0.115 | |||
| Lymphovascular invasion | ||||||
| Absence | 1 | 1 | ||||
| Presence | 2.52 | 1.54–4.11 | <0.001 | 2.41 | 1.47–3.97 | 0.001 |
| Perineural invasion | ||||||
| Absence | 1 | |||||
| Presence | NA | |||||