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Frequency of severe gastrointestinal toxicity according to number of USF1-binding sites and TSER-repeat genotypes. Gastrointestinal toxicity frequencies were stratified according to (A) the number of USF1-binding sites in the full cohort of 629 patients and (B) TSER-repeat genotype in a subcohort of 607 patients carrying only 2R or 3R polymorphisms.
