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. 2020 May 18;11(1):105–115. doi: 10.1515/tnsci-2020-0105

Figure 2.

Figure 2

miR-142-3p agomir increases SCI. (a) Expression of miR-142-3p relative to agomir-NC detected at various days in rats submitted to spinal injury following the dose of miR-142-3p agomir. *P < 0.05, **P < 0.01 compared to agomiR-NC. (b) Results of BBB score for assessing the locomotor activity at various time intervals after spinal injury following the treatment of mir-142-3p. (c) Immunohistochemistry analysis for detecting the expression of cleaved-caspase-3 in the spinal tissues after SCI (magnification at 200×). *P < 0.05, **P < 0.01 compared to sham-operated rats, P < 0.05 compared to spinal injury rats. (d) Results of the TUNEL assay for identifying extent of apoptosis of neuronal cells on the 14th day after spinal injury (magnification at 200×). The results are presented as mean ± SD.