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. 2020 May 18;11(1):105–115. doi: 10.1515/tnsci-2020-0105

Figure 3.

Figure 3

Bax is the potential target of miR-142-3p in BV-2 cells. (a) TargetScan predicted potential binding sites on the 3′UTR of Bax mRNA. (b) Quantitative results of luciferase activity of Bax-wt or mut 3′UTR in cells transfected with miR-142-3p mimics/inhibitor and NC. **P < 0.01, and P < 0.01 compared to NC. (c) Protein expression by western blot analysis. (d) Quantitative results of mRNA expression for Bax done by western blot analysis and qRT-PCR. **P < 0.01 compared to a negative control. (e) Quantitative results showing a negative correlation between expression of miR-142-3p and Bax (r = 0.961). The results are presented as mean ± SD.