Table 1.
Strain | Longitude and Latitude of Sampling | MIC (mg/L) | 3 STRAf | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 ITR | 2 VOR | Mutation in cyp51A | 2A | 2B | 2C | 3A | 3B | 3C | 4A | 4B | 4C | ||
mn224 | 35.9548° N, 52.1100° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn225 | 36.6717° N, 52.4439° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn226 | 36.6717° N, 52.4439° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn229 | 36.6717° N, 52.4439° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn227 | 36.7049° N, 52.6547° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn228 | 36.6329° N, 52.2667° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn231 | 36.4684° N, 52.8634° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn235 | 36.4684° N, 52.8634° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn232 | 36.4684° N, 52.8634° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn241 | 36.4684° N, 52.8634° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn233 | 36.6858° N, 52.5265° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn234 | 36.6858° N, 52.5265° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn236 | 36.4676° N, 52.3507° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn246 | 36.4676° N, 52.3507° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn247 | 36.5971° N, 52.6654° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn250 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn251 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn252 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn253 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn254 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn255 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn256 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn257 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn258 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn260 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn261 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn263 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn265 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn266 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn267 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn268 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn269 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn270 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn271 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn272 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn273 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn274 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn277 | 36.5659° N, 53.0586° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn279 | 36.9268° N, 50.6431° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn280 | 36.7284° N, 53.8102° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
mn281 | 36.7284° N, 53.8102° E | 16 | 2 | TR34/L98H | 22 | 10 | 9 | 9 | 9 | 23 | 8 | 10 | 8 |
IFRC: 1854 | 35.6892° N, 51.3890° E | 16 | 2 | TR34/L98H | 14 | 10 | 8 | 9 | 10 | 5 | 8 | 10 | 27 |
IFRC: 1858 | 35.6892° N, 51.3890° E | 8 | 1 | TR34/L98H | 13 | 21 | 8 | 32 | 9 | 6 | 8 | 10 | 10 |
IFRC: 1866 | 35.6892° N, 51.3890° E | 16 | 8 | TR34/L98H | 14 | 24 | 14 | 31 | 9 | 31 | 10 | 9 | 5 |
mn248 | 36.6329° N, 52.2667° E | 16 | 16 | M172V | 11 | 15 | 16 | 19 | 29 | 4 | 7 | 5 | 8 |
IFRC: 1867 | 35.6892° N, 51.3890° E | 16 | 16 | M172V | 11 | 16 | 9 | 19 | 20 | 5 | 7 | 5 | 5 |
IFRC: 1860 | 35.6892° N, 51.3890° E | 16 | 0.125 | Wild type | 27 | 18 | 16 | 7 | 12 | 28 | 27 | 5 | 8 |
IFRC: 1868 | 35.6892° N, 51.3890° E | 16 | 16 | Wild type | 27 | 18 | 16 | 7 | 12 | 28 | 27 | 5 | 8 |
IFRC: 1862 | 35.6892° N, 51.3890° E | 16 | 0.5 | Wild type | 27 | 20 | 13 | 8 | 14 | 35 | 10 | 11 | 10 |
IFRC: 1864 | 35.6892° N, 51.3890° E | 16 | 0.25 | Wild type | 20 | 10 | 8 | 37 | 9 | 6 | 10 | 9 | 15 |
IFRC: 1859 | 35.6892° N, 51.3890° E | 16 | 0.25 | Wild type | 21 | 20 | 14 | 30 | 21 | 5 | 11 | 6 | 5 |
mn245 | 36.7049° N, 52.6547° E | 16 | 1 | Wild type | 13 | 19 | 8 | 34 | 29 | 7 | 10 | 9 | 8 |
mn276 | 36.5659° N, 53.0586° E | 16 | 2 | Wild type | 18 | 22 | 15 | 43 | 13 | 27 | 13 | 8 | 10 |
mn278 | 36.5659° N, 53.0586° E | 16 | 2 | Wild type | 24 | 10 | 10 | 28 | 11 | 6 | 8 | 7 | 15 |
mn249 | 36.5659° N, 53.0586° E | 0.125 | 0.5 | Wild type | 23 | 22 | 14 | 44 | 12 | 27 | 13 | 8 | 7 |
mn223 | 36.5659° N, 53.0586° E | 0.125 | 0.5 | Wild type | 22 | 23 | 11 | 9 | 10 | 6 | 11 | 7 | 6 |
mn240 | 36.6329° N, 52.2667° E | 0.5 | 1 | Wild type | 11 | 15 | 16 | 19 | 29 | 4 | 7 | 5 | 5 |
mn242 | 36.6329° N, 52.2667° E | 0.125 | 0.5 | Wild type | 24 | 22 | 18 | 24 | 13 | 17 | 9 | 8 | 10 |
mn230 | 36.6717° N, 52.4439° E | 0.5 | 0.5 | Wild type | 24 | 20 | 18 | 22 | 10 | 6 | 9 | 12 | 9 |
IFRC: 1863 | 35.6892° N, 51.3890° E | 4 | 0.125 | Wild type | 24 | 18 | 15 | 94 | 10 | 6 | 14 | 11 | 10 |
1 ITR: itraconazole; 2 VOR: voriconazole; 3 STRAf: Short tandem repeats Aspergillus fumigatus.