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. 2020 Apr 26;10(5):823. doi: 10.3390/nano10050823

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Schematic illustration of delivery systems designed for LCP-1: polyelectrolyte complexes (PECs) and polymer-coated liposomes. PECs were produced by mixing LCP-1 with negatively charged polymer, then coated with positively charged trimethyl chitosan (TMC); while polymer-coated liposomes were produced by encapsulating LCP-1 into liposomes, followed by coating with alginate and TMC. C16: lipid moiety 2-amino-d,l-hexadecanoic acid, J8: B cell epitope derived from GAS M protein (QAEDKVKQSREAKKQVEKALKQLEDKVQ), P25: universal T helper epitope (KLIPNASLIENCTKAEL), K: lysine, S: serine.