Table 5.
Cancer | Performance statistics |
Model B1 | Model B2 | Model B3 | Model B4 | Model C1 |
---|---|---|---|---|---|---|
Breast | AIC | 34,396.10 | 34,403.29 | 34,404.73 | 34,41 1.01 | 34,410.68 |
c-Statistic | 0.800 | 0.800 | 0.799 | 0.800 | 0.800 | |
IDI | – | −0.001 (−0.003 to −0.001) | −0.002 (−0.003 to −0.001) | −0.002 (−0.003 to −0.001) | −0.002 (−0.003 to −0.001) | |
Relative IDI | – | −0.005 (−0.009 to −0.002) | −0.007 (−0.010 to −0.002) | −0.008 (−0.012 to −0.002) | −0.006 (−0.011 to −0.002) | |
Continuous NRI | – | −0.07 (−0.12 to −0.03) | −0.05 (−0.11 to −0.01) | −0.05 (−0.10 to −0.01) | −0.04 (−0.10 to −0.01) | |
Event NRI | – | −0.23 (−0.27 to −0.20) | −0.31 (−0.34 to −0.20) | −0.04 (−0.33 to −0.01) | −0.35 (−0.38 to −0.01) | |
Non-event NRI | – | 0.16 (0.14 to 0.18) | 0.26 (0.14 to 0.27) | −0.01 (−0.03 to 0.27) | 0.30 (−0.03 to 0.32) | |
Lung | AIC | 277,760.61 | 277,762.77 | 277,758.83 | 277,777.22 | 277,736.12 |
c-Statistic | 0.734 | 0.734 | 0.734 | 0.734 | 0.734 | |
IDI | – | −0.000 (−0.000 to 0.000) | −0.000 (−0.000 to 0.000) | −0.000 (−0.000 to 0.000) | 0.000 (−0.000 to 0.001) | |
Relative IDI | – | −0.000 (−0.001 to 0.001) | −0.000 (−0.001 to 0.001) | −0.001 (−0.002 to 0.001) | 0.001 (−0.001 to 0.002) | |
Continuous NRI | – | 0.03 (−0.01 to 0.08) | 0.05 (−0.00 to 0.08) | −0.04 (−0.07 to 0.08) | 0.03 (−0.07 to 0.08) | |
Event NRI | – | −0.05 (−0.06 to −0.03) | −0.02 (−0.06 to −0.00) | −0.15 (−0.16 to −0.01) | −0.37 (−0.38 to −0.01) | |
Non-event NRI | – | 0.08 (0.05 to 0.12) | 0.07 (0.03 to 0.1 1) | 0.11 (0.03 to 0.14) | 0.40 (0.03 to 0.42) | |
Colorectal | AIC | 51,526.19 | 51,527.41 | 51,526.81 | 51,528.13 | 51,508.62 |
c-Statistic | 0.783 | 0.782 | 0.782 | 0.782 | 0.783 | |
IDI | – | −0.001 (−0.001 to −0.000) | −0.001 (−0.001 to −0.002) | −0.000 (−0.001 to 0.000) | −0.000 (−0.001 to 0.001) | |
Relative IDI | – | −0.002 (−0.004 to −0.001) | −0.003 (−0.004 to −0.001) | −0.001 (−0.004 to 0.000) | −0.000 (−0.004 to 0.002) | |
Continuous NRI | – | −0.04 (−0.09 to 0.01) | −0.03 (−0.09 to 0.02) | −0.01 (−0.08 to 0.03) | −0.01 (−0.08 to 0.03) | |
Event NRI | – | −0.27 (−0.3 1 to −0.23) | −0.17 (−0.30 to −0.14) | −0.04 (−0.30 to −0.02) | 0.04 (−0.29 to 0.06) | |
Non-event NRI | – | 0.23 (0.21 to 0.26) | 0.15 (0.12 to 0.25) | 0.03 (0.01 to 0.25) | −0.04 (−0.06 to 0.25) |
AIC: Akaike information criterion; IDI: integrated discrimination improvement; NRI: net reclassification improvement; FCDS: Florida Cancer Data System. Other predictors included all the individual-level factors from the FCDS. Sex was not included as a predictor in the breast models.
Note: Values in parentheses are lower and upper bounds of 95% confidence intervals.