Table 1.
Key components of approved vaccines in the U.S. reproduced from the CDC [46].
Type of Ingredient | Example(s) | Purpose |
---|---|---|
Preservatives | Thimerosal (only in multi-dose vials of flu vaccine) | To prevent contamination |
Adjuvants | Aluminum salts * | To help boost the body’s response to the vaccine |
Stabilizers | Sugars, gelatin | To keep the vaccine effective after manufacture |
Residual cell culture materials | Egg protein | To grow enough of the virus or bacteria to make the vaccine |
Residual inactivating ingredients | Formaldehyde | To kill viruses or inactivate toxins during the manufacturing process |
Residual antibiotics | Neomycin | To prevent contamination by bacteria during the vaccine manufacturing process |
* Aluminum salts have been the only adjuvant used in most FDA-approved and licensed vaccines in the U.S.A.; other adjuvants such as ASO4, ASO1, etc. have also received FDA approval during the past decade, but not for vaccines used in children currently.