Figure 5.

The impact of mAb26 and mAb51 on in vivo ocular chlamydial infection in guinea pigs. Guinea pigs (n = 5 per group) were infected (day 0) by 1 × 10⁴ infectious forming units (IFU) of C. caviae (preincubated without/with either mAb26 or mAb51 (10 μg/mL, 1 h/RT). Upon the infection, the local treatment with the corresponding mAb (10 μg/mL, 25 μL/eye) was performed daily until day 7 post-infection. Guinea pigs were monitored until the resolution of infection (day 21). The results represent the mean of pathology score ± S.E: * p < 0.05, ** p < 0.01, *** p < 0.001.