Table 4.

Percentage of hemoglobin in the optic nerve head (ONH) analyzed using photographs of the optic nerve with the Laguna ONhE program in the mild AD and control groups.

		Control	Mild AD	Mild AD vs. Control
		(n = 49)	(n = 17)	% Mean Variation	p-Value
MMSE		30 (30–30)	23 (21–26.5)		<0.001 **
Total Hb		66.1 (62.55–70.65)	64 (55.65–73.95)	6.65	0.608
Sectors	S1	72 (67.15–77)	72.2 (56.8–79.85)	1.46	0.792
	S2	71 (66.65–75.55)	67.1 (56.6–76)	1.59	0.259
	S3	65.5 (60.95–71.5)	60.7 (56.9–72.15)	3.30	0.352
	S4	70.9 (65.95–76.1)	71.5 (58.95–79.75)	2.70	0.849
	S5	70.8 (65.4–74.4)	69.3 (56.35–75.6)	0.79	0.495
	S6	67.1 (58.75–70.1)	63.9 (55.65–69.15)	2.61	0.253
	S7	69 (63.75–73.55)	68 (60.4–78.75)	−3.11	0.901
	S8	70 (64.2–73.7)	66.9 (58.7–77.8)	−1.36	0.764
	S9	67 (58.8–70.9)	62.6 (51.75–71.9)	0.69	0.235
	S10	66.1 (57.05–72.4)	69.2 (58.15–81.5)	3.21	0.229
	S11	66.4 (61.4–70.25)	67.3 (57.4–77)	−4.31	0.553
	S12	63.6 (57.9–69.1)	63.3 (53.7–72.15)	−1.84	0.775
	S13	65 (56.45–71.1)	69.3 (56.45–81)	1.08	0.226
	S14	66.3 (60.1–70.4)	69.2 (55.4–75.05)	−4.45	0.468
	S15	62.5 (58.05–68.2)	60.2 (53.8–71.6)	−1.47	0.843
	S16	66.5 (60.8–72.85)	69.1 (57.5–79.7)	0.86	0.66
	S17	68.3 (64.15–73.85)	66.9 (58.5–79.1)	−1.86	0.965
	S18	64.8 (59.9–68.2)	65.5 (56.15–72.55)	0.56	0.665
	S19	70.1 (65.3–76.35)	69.9 (61.4–82.1)	2.01	0.883
	S20	71.1 (66.5–75.95)	71.8 (60.1–77.8)	−0.33	0.538
	S21	64.8 (59.05–71.7)	61.9 (52.8–68.8)	2.14	0.168
	S22	71.4 (65.35–78.4)	70 (57.75–83.75)	4.12	0.764
	S23	70.7 (67.1–76.15)	68.3 (57.65–74.5)	1.52	0.235
	S24	65.7 (58.45–72.25)	62.4 (53.3–69.05)	3.66	0.177

Median (interquartile range); * p < 0.05 (in bold), Mann—Whitney U test (AD: Alzheimer’s disease; vs.: versus; S: sector).