Figure 2. Anti-CRISPR (Acr) and Anti-CRISPR associated (aca) genes.
Acr proteins that have been experimentally demonstrated to prevent CRISPR interference, with representative protein accession numbers, PDB identifiers, and propensity to form homodimers. Proteins with HTH-domains, but not confirmed to form homodimers are listed as ‘Probable’. *currently under peer-review. **Acr with suggested naming convention that includes the secondary messenger.