Table 5.
Percent change (95% CIs) of thyroid hormones per 10 days of self-reported cumulative pesticide spray days from a linear mixed model * with a random intercept for subjects and days of pesticides sprayed and covariates including BMI, gender, and baseline age.
| Thyroid Hormone | Cumulative Insecticide Spray Days | p-Value | Cumulative Herbicide Spray Days | p-Value | Cumulative Fungicide Spray Days | p-Value |
|---|---|---|---|---|---|---|
| TSH | 2.92 (1.4, 4.42) | <0.001 | 4.68 (2.28, 7.07) | <0.001 | 3.28 (1.6, 4.95) | <0.001 |
| FT3 | 0.95 (0.51, 1.38) | <0.001 | 1.72 (0.01, 2.44) | <0.001 | 0.64 (0.17, 1.11) | 0.007 |
| FT4 | −0.43 (−0.79, −0.08) | 0.017 | −0.07 (−0.64, 0.49) | 0.802 | −0.58 (−0.97, −0.19) | 0.004 |
| T3 | 0.57 (−0.08, 1.22) | 0.085 | 0.18 (−0.89, 1.25) | 0.738 | 0.46 (−0.24, 1.16) | 0.197 |
| T4 | 0.06 (−0.58, 0.70) | 0.184 | 0.42 (−0.63, 1.46) | 0.435 | −0.11 (−0.81, 0.59) | 0.756 |
* Linear mixed model of Ln thyroid hormone level for all four rounds with a random intercept for subjects by conventional and organic farmers after controlling BMI, gender, and baseline age.