Figure 5.

Eggs collected from the liver or small intestine (int) of mice infected with S. mansoni for 7 weeks were incubated for 3 h at 37 °C in RPMI medium supplemented with 1% dimehyl sulfoxide (DMSO) and 15 to 500 μM of ARA. The percentage of eggs that released miracidia before (dashed lines) or after (solid lines) 1 h exposure to water and light is the mean of 2 independent experiments. All miracidia released before water and light exposure were found to be dead while miracidia released after water and light exposure were fully viable.