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. 2020 Sep 24;8(4):559. doi: 10.3390/vaccines8040559

Table 4.

Summary of BLAST search result matches between SARS-CoV-2 proteins (left-hand column) and whole bacteria at E = 1.0 (shaded left-hand columns) and E = 10.0 (unshaded right-hand columns): Bordetella pertussis (whole PERT); Mycobacterium tuberculosis (BCG); Clostridium leptum (C. lept); Escherichia coli (E. coli); Lactococcus lactis (L. lact); Lactobacillus paracasei (L. para). Note that in contrast to the LALIGN searches (Table 2 and Table 3), the BLAST searches were set to E =1 or E = 10 because of the much larger size of the entire genome as compared with the average of 17 proteins searched for the other vaccines (compare sequences in Figure 3 and Figure 4 to Figure 1 and Figure 2). Avg/Pro = average number of matches per protein.

BLAST, E = 1.0
and 10.0
Whole PERT BCG C. lept E. coli L. lact L. para Whole PERT BCG C. lept E. coli L. lact L. para
P0DTC1 Repl 1a 0 5 0 2 0 1 5 4 4 6 4 3
P0DTC2 Spike Protein 1 0 0 0 0 1 9 4 1 6 1 4
P0DTC3 Protein 3a 0 0 0 1 2 0 10 6 7 5 4 4
P0DTC4 Env Protein 0 0 0 0 0 0 2 0 2 1 0 0
P0DTC5 Memb Prot 1 0 1 1 1 1 2 6 4 6 9 10
P0DTC6 NS6 Protein 1 0 0 0 1 0 4 1 2 0 10 5
PODTC7 Protein 7a 0 0 1 1 0 1 3 2 2 5 6 3
P0DTC8 NS8 Protein 0 0 0 1 0 0 2 1 2 3 1 3
P0DTC9 Nucleoprot 1 0 0 0 0 0 7 4 1 3 2 2
P0DTD1 Repl 1ab 1 0 0 0 1 0 5 4 3 3 4 5
P0DTD2 NS9b 0 0 0 0 0 0 0 3 4 5 3 3
P0DTD3 NS Protein 14 0 0 0 0 0 0 0 1 1 3 0 2
P0DTD8 Protein 7b 1 0 0 0 0 0 6 0 0 0 0 0
Total Matches 6 5 2 6 5 4 55 36 33 46 44 42
# Proteins 3260 3997 2482 4403 2225 2708 3260 3997 2482 4403 2225 2708
Avg/Prot 0.002 0.001 0.001 0.001 0.002 0.002 0.017 0.009 0.013 0.010 0.020 0.016