Figure 10.

Dissolution profiles of CA (20 mM Ca²⁺), low Fe/Mg-CA (20 mM Ca²⁺, 5 µM Fe³⁺ and 20 mM Mg²⁺), and high Fe/Mg-CA (20 mM Ca²⁺, 25 µM Fe³⁺ and 60 mM Mg²⁺) NPs with decreasing pH. The particles were prepared in 200 µL freshly prepared DMEM media, prior to incubation at 37 °C for 30 min. Then 800 µL of DMEM media of different pHs (7.5, 7, 6.5, 6 and 5.5) was supplemented to each sample.