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DOX fluorescence intensity in the blood plasma of Balb/c 4T1 tumor-bearing mice after 24 h of intravenous injection with DOX solution, DOX-CA NPs, low DOX-Fe/Mg-CA NPs and high DOX-Fe/Mg-CA NPs for DOX solution. Results were considered significant at p-value 0.01–0.05 (*), very significant at p-value 0.001–0.01 (**). p values were calculated with respect to control (DOX in media) and treatment (DOX bound NPs). The confidence interval was 95% for the respective samples.
