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. 2020 Oct 24;10(4):189. doi: 10.3390/jpm10040189

Table 3.

Plasma BDNF concentration in asthma patients and healthy subjects carrying different BDNF Val66Met genotypes and alleles.

BDNF Val66Met
Polymorphism
Asthma Patients Healthy Subjects
Plasma BDNF Concentration (pg/mL) Median (25%; 75%) Statistical Analysis Plasma BDNF Concentration (pg/mL), Median (25%; 75%) Statistical Analysis
Genotypes AA 0.45 (0.43; 1.24) p = 0.52
Kruskal-Wallis test
0.56 (0.47; 0.65) p = 0.03
Kruskal-Wallis test *
AG 0.81 (0.52; 1.35) 0.51 (0.32; 0.73)
GG 0.94 (0.62; 0.94) 0.68 (0.49; 1.05)
Carriers A 0.80 (0.46; 1.34) p = 0.39;
U = 1544.00
Mann-Whitney test
0.51 (0.35; 0.70) p = 0.008;
U = 1089.00
Mann-Whitney test
GG 0.94 (0.62; 1.20) 0.68 (0.49; 1.05)
G 0.91 (0.61; 1.22) p = 0.37;
U = 120.50
Mann-Whitney test
0.59 (0.45; 0.93) p = 0.64;
U = 94.50
Mann-Whitney test
AA 0.45 (0.43; 1.24) 0.56 (0.47; 0.65)

BDNF = Brain-derived neurotrophic factor; * AG vs. GG, p = 0.03 Dunn’s multiple comparisons test.