Table 3.
BDNF Val66Met Polymorphism |
Asthma Patients | Healthy Subjects | |||
---|---|---|---|---|---|
Plasma BDNF Concentration (pg/mL) Median (25%; 75%) | Statistical Analysis | Plasma BDNF Concentration (pg/mL), Median (25%; 75%) | Statistical Analysis | ||
Genotypes | AA | 0.45 (0.43; 1.24) |
p = 0.52 Kruskal-Wallis test |
0.56 (0.47; 0.65) |
p = 0.03 Kruskal-Wallis test * |
AG | 0.81 (0.52; 1.35) | 0.51 (0.32; 0.73) | |||
GG | 0.94 (0.62; 0.94) | 0.68 (0.49; 1.05) | |||
Carriers | A | 0.80 (0.46; 1.34) |
p = 0.39; U = 1544.00 Mann-Whitney test |
0.51 (0.35; 0.70) |
p = 0.008; U = 1089.00 Mann-Whitney test |
GG | 0.94 (0.62; 1.20) | 0.68 (0.49; 1.05) | |||
G | 0.91 (0.61; 1.22) |
p = 0.37; U = 120.50 Mann-Whitney test |
0.59 (0.45; 0.93) |
p = 0.64; U = 94.50 Mann-Whitney test |
|
AA | 0.45 (0.43; 1.24) | 0.56 (0.47; 0.65) |
BDNF = Brain-derived neurotrophic factor; * AG vs. GG, p = 0.03 Dunn’s multiple comparisons test.