Table 2.

The biological hypotheses incorporated to the experimental design and main focuses of the collected studies.

	Genomic Structure	Epistasis	Cis-Regulatory Elements	ALS-Linked Knowledge	Functional Annotations
Vitsios et al. [103]	No	No	No	Yes	Yes
Yousefian et al. [104]	Yes	No	Yes	Yes	Yes
Bean et al. [105]	No	No	No	Yes	Yes
Yin et al. [90]	Yes	Yes	Yes	No	No
Kim et al. [91]	No	Yes	Yes	Yes	Yes
Greene et al. [107]	No	Yes	No	No	No
Sha et al. [108]	No	Yes	No	Yes	No