Table 2.
Univariable and Multivariable Survival Analysis
| HR | 95% CI | P | ||
|---|---|---|---|---|
| Lower | Upper | |||
| Univariable models | ||||
| 4-miRNA signature | 1.8 | 1.14 | 2.83 | .01 |
| MGMT promoter methylation | 0.42 | 0.26 | 0.69 | <.001 |
| Age (categorized) | 1.58 | 1.0 | 2.49 | .047 |
| Sex | 1.31 | 0.82 | 2.08 | .261 |
| Resection status | 1.39 | 0.80 | 2.42 | .238 |
| Multivariable model younger patients | ||||
| 4-miRNA signature | 1.92 | 0.94 | 3.93 | .076 |
| MGMT promoter methylation | 0.45 | 0.21 | 0.95 | .036 |
| Multivariable model older patients | ||||
| 4-miRNA signature | 1.24 | 0.65 | 2.38 | .516 |
| MGMT promoter methylation | 0.34 | 0.16 | 0.71 | .004 |