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. 2020 Dec 3;10:21090. doi: 10.1038/s41598-020-77868-4

Table 1.

Minimum biofilm inhibitory concentration (MBIC) and fractional inhibitory concentration (FIC) of R. sativus var. longipinnatus, R. sativus, and B. oleracea var. acephala extracts with proteinase K against E. coli O157:H7.

Concentration of plant extract (mg/mL) Concentration of proteinase K (µg/mL) FICI§
MBIC
of plant extract only
MBIC
of plant extract with proteinase K
FIC*
of plant extract
MBIC
of proteinase K only
MBIC
of proteinase K with plant extract
FIC
proteinase K
R. sativus var. longipinnatus 4 1 0.25 1000 100 0.1 0.35
R. sativus 4 2 0.5 1000 100 0.1 0.6
B. oleracea var. acephala 8 4 0.5 1000 200 0.2 0.7

*Fractional inhibitory concentration (FIC) was calculated from the MBIC of the combined agents divided by the MBIC of each agent alone.

§Fractional inhibitory concentration index (FICI) is the sum of the FIC of each extract and the FIC of proteinase K. The calculation was based on Odds (2003)25.