Figure 4.
Characterization of the rectal body temperature and the course of blood leukocytes after BVDV-1 challenge infection of BVDV-1b_synCP7_ΔNpro_Erns Bungo-vaccinated cattle. The animals were vaccinated with one (1x) or two (2x) shots of the candidate vaccine. (A) Mean rectal body temperature after the challenge infection. Temperatures lower than 39.5 °C are considered as physiological temperature, higher than 40 °C as fever. (B) Course of blood leukocyte counts after the challenge infection using EDTA blood as sample matrix. Mean values of the different groups are shown in percentage of the initial values (number of leukocytes measured at the day of challenge infection). The initial values (measured value at day of challenge) were set to 100%. Error bars represent standard deviations.