Table 3.

Diagnosis Characteristics of Choroidal Metastases in Seven Patients

Patients	Patient #1	Patient #2	Patient #3	Patient #4	Patient #5	Patient #6	Patient #7
Symptoms	Yes	Yes	Yes	Yes	Yes	Yes	No
Time to onset of symptoms (months)	0	0	0	0	0	0
Nature of symptoms	Myodesopsia and visual acuity loss of right eye	Intermittent visual blur on right eye	Visual acuity loss of left eye	Visual acuity loss of right eye	Blurred vision in right eye	Retro-ocular pain and visual acuity loss on right eye
Associated metastatic site (yes / no)	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Associated brain metastases	No	Yes	No	Yes	Yes	Yes	Yes
Diagnostic tool	Fundoscopic examination Fluorescein angiography B-scan ultrasound	Fundoscopic examination Fluorescein angiography B-scan ultrasound	B-scan ultrasound	Fundoscopic examination Fluorescein angiography B-scan ultrasound	Fundoscopic examination Fluorescein angiography B-scan ultrasound	B-scan ultrasound	Retrospective MRI analysis
Uni- or bilateral lesion	Unilateral	Unilateral	Unilateral	Unilateral	Bilateral	Unilateral	Unilateral
Visibility on MRI (yes / no)	Not performed	No	Yes	Yes	Yes	Yes	Yes
Response to systemic therapy	Objective response to afatinib	Objective response to afatinib	Objective response to chemotherapy	Objective response to osimertinib	No	Not evaluable	Objective response to erlotinib
Radiotherapy of choroidal metastases	No	No	No	No	Yes	No	No
Concomitant progression to visceral progression	No	No	No	No	No	Not evaluable	No

MRI magnetic resonance imaging