Table 6.
Performance Characteristics of Molecular Assays in Identifying Filarial DNA from Canine Blood and Ticks.
| Performances (in % Unless Specified) | Multiplex qPCRs Approach | Sequence Typing Approach | ||
|---|---|---|---|---|
| Ticks | Blood | Ticks | Blood | |
| True positive (n = 19) | 19 | 17 | 14 | 17 |
| True negative (n = 48) | 48 | 48 | 48 | 48 |
| False positive (n) | 0 | 0 | 0 | 0 |
| False negative (n) | 0 | 2 | 5 | 2 |
| Total | 67 | 67 | 67 | 67 |
| Sensitivity | 100 | 89.47 | 73.68 | 89.47 |
| Specificity | 100 | 100 | 100 | 100 |
| Predictive positive value (PPV) | 100 | 100 | 100 | 100 |
| Predictive negative value (PNV) | 100 | 96 | 90.57 | 96 |
| False positive rate | 0 | 0 | 0 | 0 |
| False negative rate | 0 | 4 | 9.43 | 4 |
| Correct classifcation | 28.36 | 28.36 | 28.36 | 28.36 |
| Prevalence | 28.36 | 25.37 | 20.9 | 25.37 |
| Youden index | 1 | 0.86 | 0.74 | 0.86 |