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. 2020 Oct 28;8(11):1673. doi: 10.3390/microorganisms8111673

Table 5.

Non-synonymous SNPs located in six of the 22 genes of interest that are significantly associated with AMB resistance/sensitivity based on Fisher’s Exact test (p < 0.05).

Chromosome Position Gene Amino Acid Change Predicted Effect p-Value (Fisher’s Test)
2 61,543 ERG3 Threonine to Isoleucine Missense Variant 0.01254
2 62,002 ERG3 Tyrosine to Phenylalanine Missense Variant 0.01254
2 145,934 TcsB Aspartic acid to Glycine Missense Variant 0.00081
2 146,469 TcsB Glycine to Serine Missense Variant 0.00207
2 147,363 TcsB Arginine to Glycine Missense Variant 0.00081
2 147,396 TcsB Alanine to Proline Missense Variant 0.00013
5 2,342,264 MpkC Tryptophan to Serine Missense Variant 0.00029
5 2,342,466 MpkC Isoleucine to Threonine Missense Variant 0.00003
6 857,963 CatA Aspartic acid to Asparagine Missense Variant 0.01195
6 858,366 CatA Serine to Asparagine Missense Variant 0.00007
6 2,533,399 Fos1 Alanine to Aspartic acid Missense Variant 0.04172
6 3,232,955 MpkB Lysine to Arginine Missense Variant 0.00084