Table 3.

Univariate linear regression of MMSE change per year with correction for age at death and disease duration

Variable	Standardized beta coefficient	Adjusted R2	p value
α-Synuclein in the hippocampus	− 0.914	0.774	0.001
α-Synuclein in the entorhinal cortex	− 0.972	0.892	< 0.0001
α-Synuclein in the occipitotemporal cortex	− 0.868	0.630	0.007
α-Synuclein in the prefrontal cortex	− 0.958	0.738	0.002

MMSE Mini-mental state examination