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. 2020 Dec 3;10:21206. doi: 10.1038/s41598-020-78241-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Schematic representation of the structure of Fe₃O₄/SiO₂-CUR nanocomposite containing the Fe₃O₄ core and a silica shell with curcumin molecules. (B) Transmission electron microscopy (TEM) images of the nanocomposite. Dots with 10–30 nm diameters represent Fe₃O₄ nanoparticles, the colorless borders around show SiO₂ coating, and dots < 5 nm are curcumin loaded in SiO₂. (C) The UV–visible absorption spectrum of curcumin (CUR), and Fe₃O₄/SiO₂-CUR nanocomposite. (D) VSM Magnetic measurements for synthesized Fe₃O₄ magnetite nanoparticles with the applied magnetic field sweeping from − 10 KOe to 10 KOe. (E) XRD patterns of naked Fe₃O₄, Fe₃O₄/SiO_2, and Fe₃O₄/SiO₂-CUR nanocomposite using an X-ray diffractometer.