Table 6.
Predicting factors for survival in patients with IPF assessed using a multivariate Cox hazard model including diagnosis of IP-hAF.
Variable | HR (95% CI) | p value |
---|---|---|
DLco | 0.985 (0.970–0.999) | 0.043 |
Reticulation | 2.453 (1.656–3.631) | < 0.001 |
Honeycombing | 1.767 (1.242–2.515) | 0.002 |
UIP pattern on HRCT | 1.966 (1.088–3.552) | 0.025 |
IP-hAF group | 0.522 (0.307–0.886) | 0.016 |
IPF, idiopathic pulmonary fibrosis; HR, hazard ratio; CI, confidential interval; DLco, diffusing capacity of the lung for carbon monoxide; UIP, usual interstitial pneumonia; HRCT, high-resolution computed tomography; IP-hAF, interstitial pneumonia with histologic autoimmune features.
Total lung capacity (r = 0.877; p < 0.001) was not included in the Cox proportional hazard model because of its high correlation with forced vital capacity (FVC).