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. 2020 Dec 3;10:21137. doi: 10.1038/s41598-020-78140-5

Table 6.

Predicting factors for survival in patients with IPF assessed using a multivariate Cox hazard model including diagnosis of IP-hAF.

Variable HR (95% CI) p value
DLco 0.985 (0.970–0.999) 0.043
Reticulation 2.453 (1.656–3.631) < 0.001
Honeycombing 1.767 (1.242–2.515) 0.002
UIP pattern on HRCT 1.966 (1.088–3.552) 0.025
IP-hAF group 0.522 (0.307–0.886) 0.016

IPF, idiopathic pulmonary fibrosis; HR, hazard ratio; CI, confidential interval; DLco, diffusing capacity of the lung for carbon monoxide; UIP, usual interstitial pneumonia; HRCT, high-resolution computed tomography; IP-hAF, interstitial pneumonia with histologic autoimmune features.

Total lung capacity (r = 0.877; p < 0.001) was not included in the Cox proportional hazard model because of its high correlation with forced vital capacity (FVC).