Table 2.
Canonical pathways | p value | Molecules |
---|---|---|
LXR/RXR Activation | 2.17E−07 | APOE, APOC2, PLTP, FGA, APOC3 |
FXR/RXR Activation | 2.56E−07 | APOE, APOC2, PLTP, FGA, APOC3 |
LPS/IL-1 Mediated Inhibition of RXR Function | 8.29E−05 | APOE, APOC2, PLTP, FABP5 |
Atherosclerosis Signaling | 3.66E−04 | APOE, APOC2, APOC3 |
IL-12 Signaling and Production in Macrophages | 5.67E−04 | APOE, APOC2, APOC3 |
APOC2 Apolipoprotein C2, APOC3 Apolipoprotein C3, APOE Apolipoprotein E, FABP5 Fatty acid-binding protein 5, FGA Fibrinogen alpha chain, FXR Farsenoid X receptor, IL-1 Interleukin-1, IL-12 Interleukin-12, LPS Lipopolysaccharide, LXR Liver X receptor, PLTP Phospholipid transfer protein, RXR Retinoid X receptor.