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. 2020 Dec 3;10:21033. doi: 10.1038/s41598-020-78207-3

Table 2.

Top 5 canonical pathways involved in late-onset fetal growth restriction.

Canonical pathways p value Molecules
LXR/RXR Activation 2.17E−07 APOE, APOC2, PLTP, FGA, APOC3
FXR/RXR Activation 2.56E−07 APOE, APOC2, PLTP, FGA, APOC3
LPS/IL-1 Mediated Inhibition of RXR Function 8.29E−05 APOE, APOC2, PLTP, FABP5
Atherosclerosis Signaling 3.66E−04 APOE, APOC2, APOC3
IL-12 Signaling and Production in Macrophages 5.67E−04 APOE, APOC2, APOC3

APOC2 Apolipoprotein C2, APOC3 Apolipoprotein C3, APOE Apolipoprotein E, FABP5 Fatty acid-binding protein 5, FGA Fibrinogen alpha chain, FXR Farsenoid X receptor, IL-1 Interleukin-1, IL-12 Interleukin-12, LPS Lipopolysaccharide, LXR Liver X receptor, PLTP Phospholipid transfer protein, RXR Retinoid X receptor.