Table3:
Comparison of myelin oligodendrocyte glycoprotein antibody-associated optic neuritis treatment between subjects of White and Asian race
| Treatment | White (n = 80) |
Asian (n = 73) |
Adjusted p-valuea |
|---|---|---|---|
| No acute treatment, n (%) | 3 (4) | 3 (4) | .91 |
| Acute treatment present | (n = 77) | (n = 70) | |
| Monotherapy, n (%) | 60 (78) | 67 (96) | .058b |
| IVMP, n (%) | 57 (74) | 64 (92) | |
| Oral prednisone, n (%) | 2 (3) | 3 (4) | |
| IVIG, n (%) | 1 (1) | 0 (0) | |
| Combined therapy, n(%) | 17 (22) | 3 (4) | |
| IVMP + PLEX, n (%) | 16 (21) | 3 (4) | |
| IVMP + IVIG, n (%) | 1 (1) | 0 (0) | |
| Maintenance treatment | |||
| Present, n (%) | 46 (58) | 30 (41) | .11 |
| Absent, n (%) | 34 (42) | 43 (59) |
Abbreviation: IVMP = intravenous methylprednisolone, PLEX = plasma exchange, IVIG = intravenous immunoglobulin
a
P-value for variable coefficient by generalized estimating equation (GEE) adjusting for age of onset, gender and correlation within cohort
b
P-value for comparison of monotherapy vs. combined therapy between subjects who were White and those who were Asian