Plasma pharmacokinetics of PU-H71 +/- nab-paclitaxel. Concentration-time profiles after single doses of 225 or 300 mg/m
2 PU-H71 on the PU-H71-nab-paclitaxel therapy (blue squares, n = 12) and after 180 through 300 mg/m
2 (n = 11) on the single agent PU-H71, dose escalation therapy (
NCT01393509, red squares). Values are mean ± SD.