FIG 2.
Macrophage enrichment is associated with decreased overall survival and response to adjuvant therapy, including sorafenib. (A) Multivariable analysis with hazard ratio (HR) represented as a forest plot adjusting for key covariates, including clinical and pathologic characteristics, risk factors, and immune cluster. The covariates are listed in the left column, whereas HRs, CIs, and P values are in the right column. (B) A multivariable analysis for the combination of alpha-fetoprotein (AFP) and cluster. The left column lists the various combinations, with A representing an AFP < 400 ng/mL and B representing an AFP > 400 ng/mL. The corresponding number represents the cluster. AIC, Aikake information criterion. * P = .01-.05; ** P = .001-.01; *** P = .0-.001.