Table 3.
The list of angiogenic factors and inhibitors.
| ID | Function | Name |
|---|---|---|
| VEGFD | Lymphangiogenic growth factor | Vascular endothelial growth factor D |
| PDGFD | A specific, protease-activated ligand for the PDGF beta-receptor. | Platelet-derived growth factor D |
| PDGFRA | Recruit smooth muscle cells | Platelet-derived growth factor receptor alpha |
| FGFR1, FGFR2 | Stimulate angio/arteriogenesis | Fibroblast growth factor receptor1/2 |
| FGF7, FGF12 | Stimulate angio/arteriogenesis | Fibroblast growth factor 7/12 |
| TGFBR2, TGFBR3 | Stimulate extracellular matrix production | Type II/III TGF-beta receptor |
| IL12A, IL12B | Inhibit endothelial migration. Downregulate bFGF. Induce interferon-g and IP-10 | Interleukin-12 subunit alpha/beta |
| IL12RB1, IL12RB2 | Inhibit endothelial migration. Downregulate bFGF. Induce interferon-g and IP-10 | Interleukin-12 receptor beta1/2 |
| IL10RA | Inhibit endothelial migration | Interleukin 10 receptor subunit alpha |
| IFNL1, IFNL2, IFNL3 | Inhibit endothelial migration; Downregulate bFGF | Interferon lambda 1/2/3 |