Table 3.
Time point | Group DD (n = 24) | Group MD (n = 24) | Group D (n = 24) | P value |
---|---|---|---|---|
T0 | 1 (1, 1) | 1 (1, 1) | 1 (1, 1) | 0.281 |
T10 | 3 (3, 3) | 3 (3, 3) | 2.5 (2, 3) | 0.051 |
T20 | 3 (3, 3) | 3 (3, 3) | 3 (3, 3) | 0.568 |
T30 | 3 (3, 3) | 3 (3, 3) | 3 (3, 3) | 0.571 |
T60 | 3 (3, 3) | 3 (3, 3) | 3 (3, 3) | 0.358 |
Values are presented as median (1Q, 3Q). Group DD: initial dose of 0.5 μg/kg dexmedetomidine + continuous infusion of 0.5 μg/kg/h dexmedetomidine. Group MD: initial dose of 0.02 mg/kg midazolam + continuous infusion of 0.5 μg/kg/h dexmedetomidine. Group D: continuous infusion of 0.5 μg/kg/h dexmedetomidine without initial dose. T0: start sedation, T10, 20, 30, 60: 10, 20, 30, 60 min after sedation. There were no significant differences among the groups.