Table 1. . Associations between nonintegrated and integrated CRP in dried blood spot and saliva (N = 79).
| Integration | M (SD) | 1. | 2. | 3. | 4. | 5. | 6. | 7. |
|---|---|---|---|---|---|---|---|---|
| Nonintegrated | ||||||||
| 1. DBS CRP T1 | 1.84 (2.24) | |||||||
| 2. DBS CRP T2 | 1.82 (2.21) | 0.992‡ | ||||||
| 3. sCRP T1 | 2206.41 (1334.77) | 0.183 | 0.196 | |||||
| 4. sCRP T2 | 2312.08 (1615.16) | 0.165 | 0.180 | 0.805§ | ||||
| 5. sCRP T3 | 2428.04 (1665.97) | 0.158 | 0.176 | 0.800§ | 0.958§ | |||
| 6. sCRP T4 | 2558.19 (2326.03) | 0.224† | 0.254† | 0.792§ | 0.678§ | 0.735§ | ||
| 7. sCRP T5 | 2455.53 (2886.70) | 0.211† | 0.233† | 0.823§ | 0.606§ | 0.642§ | 0.887§ | |
| 8. sCRP T6 | 2720.10 (2736.30) | 0.262† | 0.288‡ | 0.706§ | 0.574§ | 0.644§ | 0.908§ | 0.906§ |
| Integrated | 1. | 2. | 3. | 4. | ||||
| 1. Δ DBS CRP | -0.026(0.38) | |||||||
| 2. %Δ DBS CRP | -0.008(0.14) | 0.167 | ||||||
| 3. %Δ sCRP | 1.915(8.645) | 0.161 | 0.041 | |||||
| 4. AUCg sCRP | 347,542.38 (246,302.56) | 0.087 | 0.209† | 0.123 | ||||
| 5. AUCi sCRP | 33,651.78 (160,273.91) | 0.169 | 0.107 | 0.809§ | 0.236† |
Data screening involved first removing cases in which scores exceeded 3.3 standard deviations, then controlling for age and gender and finally controlling for smoking, brushing teeth and dairy consumption (df = 72). DBS is in mg/l. sCRP is in pg/ml. %Δ sCRP = percentage change in sCRP from time 1 to time 6. Significance is one tailed.
†
p < 0.05.
‡
p < 0.01.
§
p < 0.001.
AUCg: Area under the curve with respect to ground; AUCi: Area under the curve with respect to increase; DBS: Dried blood spot; sCRP: Salivary CRP; SD: Standard deviation.