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. 2020 Sep 25;15(25):2459–2474. doi: 10.2217/nnm-2020-0280

Figure 1. . Intra-rectal administration of a single dose of vasoactive intestinal peptide in sterically stabilized micelles to the colonic lumen improved bodyweight and colonic length of mice after dextran sulfate sodium insult.

Figure 1. 

(A) Schematic representation of animal study design for local nanomedicine administration in DSS colitis. (B) Bodyweight change in all treatment groups through the course of the study. (C) Representative photograph of whole excised colons of mice in all groups and graphical representation of average length per group. Data represented as mean ± SEM, n = 6.

**p < 0.005; ***p < 0.0005; ****p < 0.0001 versus control, #p < 0.05; ##p < 0.005 versus DSS; ap < 0.05 DSS-VIP-SSM versus DSS-VIP.

DSS: Dextran sulfate sodium; VIP: Vasoactive intestinal peptide; VIP-SSM: Vasoactive intestinal peptide in sterically stabilized micelles.