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. 2020 Nov 9;2(2):fcaa192. doi: 10.1093/braincomms/fcaa192

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© The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Group-level PVC tau PET uptake maps across subtyping methods using the hippocampus in the sMRI-tauPET cohort. For simplicity, only left lateral and medial views are presented since very similar results were obtained for the right lateral and medial views. Differences in tau PET uptake maps are shown in each subtype relative to HC, generated by fitting general linear model at each vertex. Cyan regions reflect greater PVC tau PET uptake in Alzheimer’s disease subtypes relative to HC. All brain maps are uncorrected for multiple comparisons at P < 0.01. HC = healthy control; HS = hippocampal-sparing; LP = limbic-predominant; MT = minimal tau; TAD = typical AD.