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(A) The Effect of GSE on the viability of OVCAR-3 cells. The cells were incubated with different concentrations (10-250 ug/mL) of GSE for 24 h. Cell viability was measured with MTT assay. Based on the results, IC50 of GSE was in the range of 71 μg/mL; (B) effect of different treatments on OVCAR-3 cells viability.***P < 0.001 indicates significant differences compared to the corresponding DMSO group GSE, Grape seed extract; DMSO, dimethyl sulfoxide.
