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. 2020 Aug 28;15(4):331–339. doi: 10.4103/1735-5362.293511

Table 3.

Effect of additives on Tobacco etch virus (TEV) protease solubility. The second column shows the percentage of impact on solubility, and this percentage could be positive or negative. The third column shows the amount of positive or negative impact on solubility. Three additives with the best effect on protein solubility (according to software analysis) are proline, CuCl2, and sodium selenite.

Additives Percent Quantity
Trehalose 2.88 -1314.93
Glycine betaine 4.46 -1636.73
Mannitol 0.08 +212.33
Sodium citrate 24.28 -3820.51
Proline 13.81 +2881.69
L-Arginine 4.39 -1625.17
Xylitol 1.31 +885.81
Sodium selenite 9.36 +2372.74
Dipotassium phosphate 23.91 -3791.31
CuCl2 11.86 +2669.86
Cetrimonium bromide 3.68 +1487.28